Pools of mutants of minimal complexity but maximal coverage of genes of interest facilitate screening for genes under selection in a particular environment.We constructed individual deletion mutants in 1,023 Salmonella enterica serovar Typhimurium genes, including almost all genes found in Salmonella but not in related genera.All mutations were con
Abstract Background Visceral adiposity indicators and the product of triglyceride and fasting plasma glucose (TyG) index-related parameters are effective surrogate markers for insulin resistance (IR) and are predictors of metabolic syndrome and diabetes mellitus.However, their genetic determinants have not been previously reported.Pleiotropic assoc
Membrane heparan sulfate proteoglycans (HSPG) regulate cell proliferation, migration, and differentiation and are therefore considered key players in cancer cell development processes.Here, we used the NT4 peptide to investigate how the sulfation pattern of HSPG on cells drives binding specificity.NT4 is a branched peptide that binds the glycosamin
The performance of machine learning algorithms is affected by the imbalanced distribution of data among Financing classes.This issue is crucial in various practical problem domains, for example, in medical diagnosis, network intrusion, fraud detection etc.Most efforts so far are mainly focused upon binary class imbalance problem.However, the class
Dalam bernyanyi sistem pernapasan adalah salah satu bagian penting.Penelitian ini bertujuan untuk mengetahui adanya pengaruh permainan akuatik terhadap sistema respirasi, apakah dapat meningkat atau tidak pada anggota UKM PSM Sinfonia Universitas Muhammadiyah Sukabumi.Bentuk penelitian ini menggunakan kuantitatif dengan bentuk metode eksperimen dan